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Research Areas and Aims
Our main research focus is on the brain mechanisms underlying language and other cognitive functions. We are particularly interested in the functional interaction of the two cerebral hemispheres in healthy persons as well as in patients with psychiatric (autism spectrum disorders, schizophrenia) or neurological (aphasia) conditions. Methodologically, we use a wide range of neuropsychological and behavioural techniques and neuroimaging methods (EEG, fMRI, MEG) to investigate neurobiological correlates of cognitive processes.
We follow a translational neuroscience approach with the aim to use insights into the brain mechanisms of cognition in neuropsychiatric conditions to develop new diagnostic tools and therapeutic interventions.
The main clinical-therapeutic focus of our group is on the neurorehabilitation and functional restitution of language in stroke patients with chronic aphasia. In collaboration with colleagues at the Freie Universität Berlin, we are further developing and testing intensive language action therapy (ILAT), a fairly novel and highly effective method for treating communication difficulties in aphasia. In this context, we are exploring the effects of cognitive and psychological variables on functional language recovery and post stroke depression.
Current Research Projects
- Neuroimaging (EEG, MEG, fMRI) and functional lateralization of language
- Cognitive and motor processing in autism spectrum disorders
- Aphasia Therapy, Neurorehabilitation and cortical reorganisation after stroke
- Poststroke depression
- Mohr, B. 2017. Neuroplasticity, functional ecovery and intensive language therapy in chronic post stroke aphasia: Which factors are relevant? Frontiers in Human Neuroscience, 11:332. doi.org/10.3389/fnhum.2017.00332
- Mohr, B., MacGregor, L.J., Difrancesco, S., Pulvermüller, F., Shtyrov, Y. 2016. Therapy induced left-hemispheric changes in word-specific brain activation in aphasia: Evidence from magnetoencephalography. Neuropsychologia, 93, 413-424.
- Lucchese, G., Stahl, B., Dreyer, F., Pulvermüller, F. & Mohr, B. 2016. Therapy-Induced Neuroplasticity of Language in Chronic Post Stroke Aphasia: A Mismatch Negativity Study of (A) Grammatical and Meaningful/less Mini-Constructions. Frontiers in Human Neuroscience, 10:669. doi: 10.3389/fnhum.2016.00669
- Stahl, B., Mohr, B., Dreyer, F., Lucchese, G., Pulvermüller, F. 2016. Language therapy in social interaction: Communication mechanisms promote recovery from chronic aphasia. Cortex, 85, 90-99.
- Moseley, R.L., Correia, M.M., Baron-Cohen, S., Shtyrov, Y., Pulvermüller, F. Mohr, B. 2016. Reduced volume of the arcuate fasciculus in adults with high-functioning autism spectrum conditions. Frontiers in Human Neuroscience, 10:214. doi: 10.3389/fnhum.2016.00214.
- Moseley, R., Shtyrov, Y., Mohr, B., Lombardo, M.V., Baron-Cohen, S., Pulvermüller, F. 2015. Lost for emotion words: What motor and limbic brain activations reveal about autism and about semantics in general. Neuroimage, 104, 413-422.
- MacGregor, L., Difrancesco, S., Pulvermüller, F., Shtyrov, Y., Mohr, B. 2015. Ultra-rapid access to words in chronic aphasia: The effects of intensive language action therapy (ILAT) Brain Topography, 28, 279-291.
- Mohr, B., Difrancesco, S., Harrington, K., Evans, S., Pulvermüller, F. 2014. Increase of right-hemispheric activation after intensive language action therapy (ILAT) in chronic aphasia: fMRI evidence from auditory semantic processing. Frontiers in Human Neuroscience, 14, doi: 10.3389/fnhum.2014.00919.
- Moseley, R., Carota, F., Hauk, O., Mohr, B., Pulvermüller, F. 2012. A Role for the Motor System in Binding Abstract Emotional Meaning. Cerebral Cortex, 22, 1634-1647.
- Mohr, B., Pulvermüller, F., Rockstroh, B., Endrass, T. 2008: Hemispheric cooperation –A crucial factor in schizophrenia? Neurophysiological evidence. Neuroimage, 41, 1102-1110.
Downloads of publications are available here: